The Guerriero Lab aims to design clinically effective strategies to promote T-cell activation and weaken the immune-suppressive tumor microenvironment to improve immunotherapy response rates in breast cancer patients. We seek to identify tumor-promoting tumor macrophages in breast tumors before and after therapy, elucidate their molecular and metabolic regulation that promotes immune suppression and therapy-resistance and determine how tumor macrophage phenotype, metabolism and function can be modulated for anti-tumor responses.
CIMT Annual Meeting
It was a privilege to present our research at the Association for Cancer Immunotherapy (CIMT) conference this year in Mainz Germany. It was a fantastic three days of great talks…
CIHR Fellowship
Congratulations to Adam Nelson on winning a 2023 Canadian Health Institute of Research Fellowship for his project targeting macrophages in breast cancer! Congratulations and well deserved!
Department of Surgery Faculty Convener
Congratulations to Dr. Jennifer Guerriero on her new appointment as the Department of Surgery Faculty Convener! Through this role she will serve as a liaison to foster communication between department…