GUERRIERO LAB

Accelerating breast cancer immunotherapy by
harnessing tumor associated macrophages

The Guerriero Lab aims to design clinically effective strategies to promote T-cell activation and weaken the immune-suppressive tumor microenvironment to improve immunotherapy response rates in breast cancer patients. We seek to identify tumor-promoting tumor macrophages in breast tumors before and after therapy, elucidate their molecular and metabolic regulation that promotes immune suppression and therapy-resistance and determine how tumor macrophage phenotype, metabolism and function can be modulated for anti-tumor responses.

RECENT NEWS
25Mar 25

Guerriero Lab at AACR-Dr.Nelson

Congratulations to Dr. Nelson, who was awarded a Scholar-In-Training Travel Award for AACR 2025. Dr. Nelson will be presenting a poster titled: "Combined anti-CSF-1R and anti-TIM-3 overcome immune-mediated mechanisms of…

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25Mar 25

Guerriero Lab at AACR-Dr.Shimada

Congratulations to Dr. Kenichi Shimada who was selected to give a talk at AACR 2025 titled: "An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive…

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