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Accelerating breast cancer immunotherapy by
harnessing tumor associated macrophages.

The Guerriero Lab aims to design clinically effective strategies to promote T-cell activation and weaken the immune-suppressive tumor microenvironment to improve immunotherapy response rates in breast cancer patients. We seek to identify tumor-promoting tumor macrophages in breast tumors before and after therapy, elucidate their molecular and metabolic regulation that promotes immune suppression and therapy-resistance and determine how tumor macrophage phenotype, metabolism and function can be modulated for anti-tumor responses.

17May 23

Molecular and Cellular Oncology Retreat

Fantastic poster presentations by Kenichi and Dan at the DanaFarber Molecular and Cellular Oncology Retreat. They both presented new stories and data on elucidating mechanisms of therapy¬† resistance in breast…

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