The Guerriero Lab aims to design clinically effective strategies to promote T-cell activation and weaken the immune-suppressive tumor microenvironment to improve immunotherapy response rates in breast cancer patients. We seek to identify tumor-promoting tumor macrophages in breast tumors before and after therapy, elucidate their molecular and metabolic regulation that promotes immune suppression and therapy-resistance and determine how tumor macrophage phenotype, metabolism and function can be modulated for anti-tumor responses.
Guerriero Lab at SITC 2023
The Guerriero Lab joined thousands of other researchers in San Diego for SITC 2023. It was full of great talks and discussions. Congratulations to Carlos and Adam for winning the…
Guerriero Lab Anniversary
Today is the Guerriero Lab's 3rd year anniversary! Thank you to all of our members and collaborators over the last three years. Here is to many more successful years of…
Congratulations Adam on winning the 2023 John A. Mannick Research Award
Congratulations to Dr. Adam Nelson on winning a 2023 John A. Mannick Research Award for his work in targeting macrophages during PARP inhibitor therapy. Adam presented his work at the…